Former Hearts of Oak and TP Mazembe playmaker, Torric Jibril and Real Mallorca midfielder Iddrisu Baba earned call up to join the team.
They will play South Africa on Thursday, 14th November 2019 before playing Sao Tome three days later.
Below is the full Black Stars squad announced for the two games
GOALKEEPERS: Richard Ofori (Maritzburg FC, South Africa), Felix Annan (Asante Kotoko, Ghana), Razak Abalora (Azam FC, Tanzania)
Andy Yiadom (Reading, England), Harrison Afful (Columbus Crew, USA), Lumor Agbenyenu (Real Mallorca, Spain), Joseph Aidoo (Celta Vigo, Spain), Joseph Aidoo (Celta Vigo, Spain), Kassim Nuhu (Fortuna Dusseldorf, Germany), Nicholas Opoku (Udinese, Italy), Mohammed Salisu (Real Valladolid, Spain)
Samuel Owusu (Al Fahya, Saudi Arabia), Thomas Partey (Atletico Madrid, Spain), Alfred Duncan (Sassuolo, Italy), Mubarak Wakaso (Deportivo Alaves, Spain), Iddrisu Baba (Real Mallorca, Spain), Christopher Antwi-Adjei (SC Paderborn, Germany)
Andre Ayew (Swansea, England), Mohammed Kudus (FC Nordsjaelland, Denmark), Emmanuel Boateng (Dalian Yifang, China), Jordan Ayew (Crystal Palace, England), Torric Jibril (TP Mazembe, DR Congo), Shafiu Mumuni (Ashantigold)